常州大学英国威廉希尔公司生物与食品工程学院

Email：zhangdd@cczu.edu.cn

通讯地址：江苏省常州市武进区科教城常州大学测试楼A817

研究方向

基于暗场散射成像的癌症相关酶检测方法研究

教育和工作经历

2022.09−至今          常州大学生物与食品工程学院

2018.09−2022.06         东南大学                 材料物理与化学             博士

2016.01−2018.06         中国药科大学天然药物活性组分与药效国家重点实验室联合培养

2015.09−2018.06         广东药科大学             中药学                     硕士

2011.09−2015.06         南京中医药大学           制药工程                   本科

发表论文和专利

发表论文：

1.       Duoduo Zhang^#, Nan Jiang^#, Peng Li, Yusheng Zhang, Shihao Sun, Jian Mao, Songqin Liu, Wei Wei^*. Detection of Monoamine Oxidase B Using Dark-field Light Scattering Imaging and Colorimetry. Chemical Communications, 2022, doi: 10.1039/d2cc05139g .

2.       Duoduo Zhang, Wei Wei^*, Yong Liu, Yuepu Pu, Songqin Liu. Dual Imaging of Poly(ADP-ribose) Polymerase-1 and Endogenous H₂O₂ for the Diagnosis of Cancer Cells Using Silver-Coated Gold Nanorods. Analytical Chemistry, 2021, 93(48), 16248−16256.

3.       Duoduo Zhang, Kan Wang, Wei Wei^*, Yong Liu, Songqin Liu. Multifunctional Plasmonic Core-Satellites Nanoprobe for Cancer Diagnosis and Therapy Based on a Cascade Reaction Induced by MicroRNA. Analytical Chemistry, 2021, 93(27), 9521−9530.

4.       Duoduo Zhang, Kan Wang, Wei Wei^*, Songqin Liu. Single-Particle Assay of Poly(ADP-ribose) Polymerase-1 Activity with Dark-Field Optical Microscopy. ACS Sensors, 2020, 5(4), 1198−1206.

5.        Yanhua Tang^#, Duoduo Zhang^#, Ye Lu, Songqin Liu, Juan Zhang, Yuepu Pu, Wei Wei^*,Fluorescence Imaging of FEN1 Activity in Living Cells Based on Controlled-Release of Fluorescence Probe from Mesoporous Silica Nanoparticles. Biosensors & Bioelectronics, 2022, 214, 114529. (共同一作)

6.       Chen Zong^#*, Duoduo Zhang^#, Fan Jiang, Hua Yang, Shijia Liu, Ping Li^*. Metal-enhanced chemiluminescence detection of C-reaction protein based on silver nanoparticle hybrid probes. Talanta, 2019, 199, 164−169. (共同一作)

7.       Chen Zong^#, Duoduo Zhang^#, Hua Yang, Shumei Wang, Ming Chu, Ping Li^*. Chemiluminescence immunoassay of cardiac troponin T by using silver nanoparticles functionalized with hemin/G-quadruplex DNAzyme on a glass chip array. Microchimica Acta, 2017, 184(9), 3197−3204. (共同一作)

8.       张多多, 宗晨, 王淑美, 李萍^*. 基于银纳米粒子催化鲁米诺-过氧化氢化学发光体系测定丹参酮IIA磺酸钠, 分析测试学报, 2017, 36(10), 1245−1249.

9.       张多多, 韩秀娟, 侯雪峰, 汪刚, 顾俊菲, 宋捷, 封亮^*, 贾晓斌^*. 生物等效性研究方法及其在中药制剂产品中的应用, 中草药, 2016, 47(20), 3712−3719.

专利授权：

1.     李萍, 宗晨, 张多多, 杨华. 一种测定C反应蛋白的化学发光免疫方法. 授权公告号: CN 109298187 B, 授权公告日: 2020.01.10.

2.     卫伟, 张多多, 刘松琴. 基于暗场散射成像的PARP-1单粒子检测方法. 授权公告号: CN 111024624 B, 授权公告日: 2022.04.26.